Waiting for the Other Shoe to Drop
That seemed to shift when Apoquel came out. Magically less itchy, often within hours of a pill!
More expense, less results for your itchy dog.
The New Drug on the Block: Get Mabbed
Pictures of evil vets rushing at your dog with syringes drawn…)
Get Out Your Credit Card
It’s an injectable drug, so it’ll be vet-only, and yep, it’s expensive.
So, if you sign up for this new wonder drug, plan on using it monthly, for life:
A Single Purpose Silver Bullet?
That messenger molecule, inherent in mammalian immune systems, is called IL-31.
Interleukin 31 is classed as a cytokine, and when they injected it into dogs, the dogs got itchy.
Or, might there be some unintended consequences of messing with Mom Nature?
That just means this ain’t no one trick pony.
Wait, pathogens? Those are disease-causing organisms, aka viruses and bacteria and yeasts, right?
So, IL-31’s “main role” is helping us fight the bad guys?
Oh oh. Cytokine interferes with fighting the disease causers?
What else is this drug interfering with?
- Red blood cells to carry the oxygen
- Various white blood cells to fight disease (T and B cells, natural killer cells, etc.)
- Platelets, which help us clot after injury
So, Is Cytopoint Safe?
That’s the $40K question, isn’t it?
Apoquel wasn’t deemed safe for dogs under 1 year of age. Cytopoint?
(WF Note: Why are young dogs affected? Experts aren’t even asking this…)4
The study that brought the drug to market was only carried out for seven months.
On 36 laboratory Beagles. A curious species that seems highly resistant to disease.
Definitely not representative of the average dog in the world, as these dogs never leave the lab.
Are you feeling safe now?
Their in-house study, on 36 lab Beagles, ran for 7 whole months, and there were no problems.
“Let’s get this on the market, boys! No one will notice how small our study was or how short!
Crystal Ball Time
I’m not impressed.
Or two or three or, umm, LIFE?
So, time to rub the dust off my crystal ball and take a look…
And the part about regulating blood cell production?
I think it’s safe to say this one, like most designer drugs, will come back to bite us.
- More susceptibility to parvo, distemper, or dog flu?
- Immune deficiency diseases from impaired white blood cell production?
I don’t know if any of this will come about, but does anyone?
The Big Why
Or pollen. Or grass. Or chicken.
Things that have been on the planet for a very long time.
And things that not every dog has a hard time with.
It’s the vaccines. That history goes back to at least 1884.
Tell us Your Story
Have an itchy, allergic dog?
Will you be using this new wonder drug called Cyptopoint?
Or are you already? How’s it gone so far?